Enter the following command and hit enter:.

Open Terminal (Applications > Utilities).

And it further appears that verifying and repairing Disk Permissions via Terminal may fix this. It appears that it is a known problem that, after upgrading, some Office versions do not open.

If you still cannot open the file even after all of the add-ins are disabled, then add-ins are not causing this.

Try enabling add-ins one by one until you find the one that is causing this. And open the file? Can you open the file without any issue? If so, then, one of the add-ins is causing this. See this article if you cannot open Pages files.

Click Pages (Word), Numbers (Excel), or Keynote (PowerPoint), depending on the type of the file.

If you are having this problem with only certain files, you may try the following workaround. Simply open an Office app and go to Help > Check for Updates. You can update your Mac by going to System Preferences > Software Update.

Ensure that your Mac has the latest version of macOS.

Test your problem in Safe Mode and then exit Safe Mode and test your problem again.

Restart your Mac: You can restart your Mac by going to the Apple menu > restart.

Restart the app: First quit the app (Command, q or click Excel > Quit Excel, Quit Word, or Quit PowerPoint), and then try to open your file.

In this article, we explain how you can troubleshoot the Office problems on your Mac. If you are having this problem, you will not be able to view, edit, or create Office files on your Mac. For example, when they want to open an Excel file, the file crashes, freezes, or won’t open at all. Several users have reported that they could not open their Microsoft Office (Excel, Word, PowerPoint, etc) files on the Mac.

Open office xlsx